There are many options available when selecting an RSS reader (see this extensive directory of readers). Here is a select sample of popular readers:
Web-Based: No downloading or installation required. You can access your feeds from different computers.
Client-Based: Downloaded and installed on the desktop. You can download your RSS feeds to read offline.
Browser-Based: Add RSS feeds right into your browser.
This guide will help you use Feeds in Lotus Notes and Google Reader, the most popular RSS reader.
Here are a few icons regularly used to locate RSS feeds:
If you see a button for the reader you use, simply click on it to subscribe to the feed.
Lotus Notes has built in RSS support so you can use it as a feed reader. You may want to consider doing this if you want a universal inbox for email and RSS feeds.
See: Feeds in Lotus Notes